Mechatronic Engineer – Cryo-EM Technology Development (Part-time)

The EMBL Imaging Centre is seeking a Mechatronic Engineer to join our technology development activities at the interface of engineering, robotics and cryo-electron microscopy (cryo-EM). Two unique prototype instruments, EasyGrid and EasyGrid Control, have recently been deployed at the EMBL Imaging Centre in Heidelberg, enabling the automated preparation and quality control of samples for cryo-electron microscopy and cryo-electron tomography. The instruments combine multi-axis robots, light and holographic microscopy, cryogenic storage systems, an atmospheric plasma generator, and humidity- and temperature-controlled compartments. You will play a central role in the development of EasyGridNext, a next-generation platform for automated and reproducible cryo-EM sample preparation and dynamic on-grid experiments.

• Lead and contribute to the engineering development and implementation of EasyGridNext, with a focus on reliability, robustness and service readiness.
• Design, prototype, integrate and test mechatronic subsystems, including microfluidic handling, temperature and humidity control, cryogenics, as well as a range of sensors and actuators.
• Contribute to the integration of hardware, software and experimental metadata into reliable and traceable workflows.
• Implement modular hardware for time-resolved fluid delivery and the study of dynamic biochemical reactions.
• Work with biological researchers to translate experimental requirements into engineering specifications and practical solutions.
• Contribute to the transition of prototypes into documented, maintainable and user-facing scientific infrastructure.
• Support the deployment of the resulting technology within the EMBL Imaging Centre and, ultimately, its use by the wider scientific community.

• A degree in Electrical Engineering, Mechatronics, Mechanical Engineering, Robotics, Automation Engineering or a related engineering discipline, or an equivalent combination of education, training and experience.
• Practical experience in instrument development, mechatronic systems, motion control, machine vision, robotics or automation.
• A good understanding of relevant physical principles, including temperature, humidity, cryogenics, microfluidics, pneumatics, etc.
• Experience with CAD, rapid prototyping, machining or additive manufacturing.
• Strong problem-solving skills and a practical, hands-on approach to developing and improving complex technical systems.
• The ability to work independently while collaborating effectively with scientists and engineers from different disciplines.
• Excellent communication and organisational skills, with the ability to translate scientific requirements into technical specifications and practical engineering solutions.
• Experience in developing robotic or automated laboratory equipment.
• Experience with software development for scientific instrumentation, user interface development or object-oriented programming (e.g. Java).
• Experience in fluidics, precision dispensing or microfluidic systems.